Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 5/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938688 | 0.90 | GPR183 (0.65) | LMNAMAPK1RAB9AGRM5AR | |
| SCHEMBL2474223 | 0.85 | AR (0.64) | LMNAMAPK1RAB9AGRM5AR | |
| SCHEMBL19823672 | 0.83 | AR (0.61) | MAPK1GRM5ARHPGDUSP2 | |
| SCHEMBL24416093 | 0.81 | AR (0.60) | RAB9AGRM5ARHPGDUSP2 | |
| SCHEMBL4563425 | 0.81 | LMNA (0.62) | LMNAMAPK1RAB9AGRM5HPGD | |
| SCHEMBL252026 | 0.80 | HPGD (0.79) | LMNAMAPK1HPGDUSP2ALDH1A1 | |
| SCHEMBL7129676 | 0.80 | HPGD (0.79) | LMNAMAPK1HPGDUSP2ALDH1A1 | |
| SCHEMBL17954064 | 0.79 | GRM5 (0.62) | LMNAMAPK1RAB9AGRM5HPGD | |
| SCHEMBL2342238 | 0.79 | AR (0.57) | GRM5ARUSP2ALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1597472 | 0.78 | HPGD (0.76) | LMNAMAPK1HPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160214951-A1 | EBI2 MODULATORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214951-A1 | EBI2 MODULATORS | BIRC2, HAVCR2, MAVS | LMNA 2951/4885MAPK1 2264/4885RAB9A 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.