Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.54 |
| ▸ | ELOC | Q15369 | 7/20 | 0.49 |
| ▸ | ELOB | Q15370 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26384478 | 0.89 | VHL (0.59) | VHLELOCELOB | |
| SCHEMBL25006762 | 0.84 | VHL (0.56) | VHLELOCELOB | |
| SCHEMBL26384482 | 0.84 | VHL (0.56) | VHLELOCELOB | |
| SCHEMBL26384486 | 0.83 | HRH3 (0.59) | VHLELOCELOB | |
| SCHEMBL25007827 | 0.81 | VHL (0.53) | VHLELOCELOB | |
| SCHEMBL26384479 | 0.79 | VHL (0.51) | VHLELOCELOB | |
| SCHEMBL17954398 | 0.76 | VHL (0.44) | VHLELOCELOB | |
| SCHEMBL26386622 | 0.76 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL23912484 | 0.76 | ACHE (0.48) | — | |
| SCHEMBL25008393 | 0.74 | VHL (0.57) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016118666-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF THE ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2016-07-28 | — | — | WO | disclosed |