Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | RB1 | P06400 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2731922 | 0.84 | ACHE (0.61) | ACHEBACE1BCHERB1RAB9A | |
| SCHEMBL1845568 | 0.83 | GRIN2B (0.54) | ACHEBACE1BCHERAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL27669852 | 0.82 | RAB9A (0.61) | ACHEBACE1BCHERB1RAB9A | |
| SCHEMBL11438708 | 0.81 | TSHR (0.56) | ACHEBACE1BCHERB1RAB9A | |
| SCHEMBL11434269 | 0.77 | HRH3 (0.69) | ACHEBACE1BCHERAB9AMEN1 | |
| SCHEMBL31630353 | 0.76 | ACHE (0.45) | ACHEBACE1BCHERB1RAB9A | |
| SCHEMBL17954398 | 0.76 | VHL (0.44) | RAB9AMEN1KMT2AHRH3LTA4H | |
| SCHEMBL17954402 | 0.76 | VHL (0.54) | — | |
| SCHEMBL17954409 | 0.76 | HDAC1 (0.36) | RAB9AMEN1KMT2AHRH3LTA4H | |
| SCHEMBL22255219 | 0.76 | ACHE (0.54) | ACHEBACE1BCHERB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |