Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 11/20 | 0.46 |
| ▸ | RBP4 | P02753 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17955466 | 1.00 | HTR2C (0.51) | HTR2CHTR2BUTS2RRBP4KMT2A | |
| SCHEMBL17955438 | 0.93 | KMT2A (0.44) | HTR2CHTR2BUTS2RRBP4KMT2A | |
| SCHEMBL17955447 | 0.84 | SLC6A4 (0.43) | HTR2CHTR2BRBP4 | |
| SCHEMBL17955442 | 0.84 | SLC6A4 (0.43) | HTR2CHTR2BRBP4 | |
| SCHEMBL17955427 | 0.82 | RBP4 (0.52) | HTR2CHTR2BUTS2RRBP4 | |
| SCHEMBL17955424 | 0.82 | RBP4 (0.41) | HTR2CHTR2BUTS2RRBP4 | |
| SCHEMBL16559749 | 0.82 | RBP4 (0.52) | HTR2CHTR2BRBP4KMT2A | |
| SCHEMBL17955443 | 0.82 | GPR6 (0.43) | RBP4 | |
| SCHEMBL15062015 | 0.81 | HTR2C (0.54) | HTR2CHTR2BKMT2A | |
| SCHEMBL15062023 | 0.81 | HTR2C (0.54) | HTR2CHTR2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403835-B2 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | ARES TRADING S.A. (CH) | 2016-08-02 | — | — | US | disclosed |
| US-9403835-B2 | Tetraaza-cyclopenta[a]indenyl and their use as positive allosteric modulators | ARES TRADING S.A. (CH) | 2016-08-02 | — | — | US | disclosed |