Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136073 | 0.92 | KDM4E (0.38) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17955923 | 0.91 | KDM4E (0.41) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2105872 | 0.91 | NPC1 (0.46) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17955988 | 0.90 | F7 (0.39) | F2F7F3TP53 | |
| SCHEMBL17955940 | 0.89 | KDM4E (0.40) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17955937 | 0.89 | KDM4E (0.40) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17955956 | 0.88 | F2 (0.44) | F2F7F3PRSS1PRSS2 | |
| SCHEMBL9980441 | 0.88 | NPC1 (0.44) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9980465 | 0.88 | KDM4E (0.47) | KDM4EHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17955989 | 0.87 | F2 (0.38) | ALDH1A1F2F7F3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050875-B1 | NOVEL IMIDAZOLE DERIVATIVE AND THERAPEUTICAL USE THEREOF | UNIV YONSEI IACF (KR) | 2019-03-13 | — | — | EP | disclosed |
| US-20160297768-A1 | NOVEL IMIDAZOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-10-13 | — | — | US | disclosed |
| US-20160297768-A1 | NOVEL IMIDAZOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-10-13 | — | — | US | disclosed |
| EP-3050875-A1 | NOVEL IMIDAZOLE DERIVATIVE AND THERAPEUTICAL USE THEREOF | Industry-Academic Cooperation Foundation, Yonsei University (KR) | 2016-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297768-A1 | NOVEL IMIDAZOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | TP53, BAD, API5 | KDM4E 1678/4885HTT 3915/4885SMN1; SMN2 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.