SCHEMBL17958889

SCHEMBL17958889

CC(=O)OC1O[C@](CF)(COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H]1OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.36
▸ LMNA P02545 2/20 0.35
▸ PRKCA P17252 1/20 0.35
▸ CYP2D6 P10635 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ GSTP1 P09211 2/20 0.34
▸ METAP2 P50579 2/20 0.33
▸ NT5E P21589 1/20 0.33
▸ CAPN1 P07384 1/20 0.33
▸ BCHE P06276 1/20 0.33
▸ CYP2C9 P11712 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21418923 1.00 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL6834854 1.00 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL30590044 1.00 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL23152976 0.90 ALDH1A1 (0.37) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL20756448 0.90 ALDH1A1 (0.37) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL25400002 0.89 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL25400006 0.89 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL25400372 0.89 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL1098278 0.89 ALDH1A1 (0.42) ALDH1A1LMNAPRKCACYP2D6MAPK1
SCHEMBL30689531 0.89 ALDH1A1 (0.36) ALDH1A1LMNAPRKCACYP2D6MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 — — EP disclosed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
US-20260053838-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDES AND NUCLEOSIDES FOR TREATING VIRAL INFECTIONS UNIV EMORY (US) 2026-02-26 — — US disclosed
US-12414961-B2 Substituted nucleosides and nucleotides for treating viral infections EMORY UNIVERSITY (US) 2025-09-16 — — US disclosed
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO EMORY UNIVERSITY 2025-09-11 — — US disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS EMORY UNIVERSITY 2024-05-30 — — US disclosed
CN-117881402-A Nucleotide and nucleoside therapeutic compositions, combinations, and uses related thereto 埃默里大学 2024-04-12 — — CN disclosed
EP-4333859-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO Emory University (US) 2024-03-13 — — EP disclosed
US-11857560-B2 Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections EMORY UNIVERSITY (US) 2024-01-02 — — US disclosed
EP-4094767-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2022-11-30 — — EP disclosed
US-20220296626-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY 2022-09-22 — — US disclosed
EP-3043803-B1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES UNIV EMORY (US) 2022-04-27 — — EP disclosed
US-11166973-B2 Substituted nucleotides and nucleosides for treating viral infections EMORY UNIVERSITY (US) 2021-11-09 — — US disclosed
US-20190298750-A1 Nucleotide and Nucleoside Therapeutic Compositions and Uses Related Thereto DEFENSE THREAT REDUCTION AGENCY, US DOD 2019-10-03 — — US disclosed
US-10202412-B2 β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections Atea Pharmaceuticals, Inc. (US) 2019-02-12 — — US disclosed
US-10149859-B2 Nucleotide and nucleoside therapeutic compositions and uses related thereto EMORY UNIVERSITY (US) 2018-12-11 — — US disclosed
WO-2016145142-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTICS COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2016-09-15 — — WO disclosed
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO DEFENSE THREAT REDUCTION AGENCY, US DOD 2016-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, NTPCR, TYMP ALDH1A1 1897/4885LMNA 2417/4885PRKCA 2823/4885
US-10149859-B2 Nucleotide and nucleoside therapeutic compositions and uses related thereto PNP, NTPCR, TYMP ALDH1A1 1897/4885LMNA 2417/4885PRKCA 2823/4885
US-20220296626-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, NTPCR, TYMP ALDH1A1 1897/4885LMNA 2417/4885PRKCA 2823/4885
US-11166973-B2 Substituted nucleotides and nucleosides for treating viral infections PNP, TYMP, HPRT1 ALDH1A1 996/4885LMNA 2780/4885PRKCA 2782/4885
US-11857560-B2 Pharmaceutical compositions comprising substituted nucleotides and nucleosides for treating viral infections SLC28A1, PNP, SLC28A2 ALDH1A1 1819/4885LMNA 1285/4885PRKCA 1972/4885
US-20260053838-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDES AND NUCLEOSIDES FOR TREATING VIRAL INFECTIONS DCTD, RNMT, NSUN2 ALDH1A1 1815/4885LMNA 1339/4885PRKCA 1214/4885
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO NTPCR, TYMP, MTAP ALDH1A1 2547/4885LMNA 2827/4885PRKCA 3694/4885
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS PNP, NTPCR, TYMP ALDH1A1 1853/4885LMNA 2528/4885PRKCA 2236/4885
US-12414961-B2 Substituted nucleosides and nucleotides for treating viral infections PNP, NTPCR, TYMP ALDH1A1 2180/4885LMNA 2334/4885PRKCA 1729/4885
US-10202412-B2 β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections MTAP, NSUN2, PNP ALDH1A1 3498/4885LMNA 1832/4885PRKCA 2395/4885
US-20190298750-A1 Nucleotide and Nucleoside Therapeutic Compositions and Uses Related Thereto PNP, NTPCR, TYMP ALDH1A1 1897/4885LMNA 2417/4885PRKCA 2823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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