Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31199125 | 0.73 | CALM1 (0.44) | CALM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29585113 | 0.67 | CALM1 (0.41) | CALM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31257100 | 0.67 | CALM1 (0.41) | CALM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11523704 | 0.66 | CALM1 (0.58) | CALM1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6292566 | 0.66 | TYMP (0.49) | MEN1KMT2AALDH1A1TYMPCTRC | |
| SCHEMBL11521959 | 0.64 | CALM1 (0.55) | CALM1MEN1KMT2AALDH1A1HPGD | |
| Diphenylmethane SCHEMBL4361124 | 0.64 | CALM1 (1.00) | CALM1ALDH1A1HPGDCYP3A4ALOX15 | |
| Diphenylmethane SCHEMBL14763944 | 0.64 | CALM1 (1.00) | CALM1ALDH1A1HPGDCYP3A4ALOX15 | |
| Diphenylmethane SCHEMBL1303 | 0.64 | CALM1 (1.00) | CALM1ALDH1A1HPGDCYP3A4ALOX15 | |
| Diphenylmethane SCHEMBL3792579 | 0.64 | CALM1 (1.00) | CALM1ALDH1A1HPGDCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016119052-A1 | COMPOSITIONS AND METHODS FOR ENHANCING ONCOLYTIC VIRUS EFFICACY | OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) | 2016-08-04 | — | — | WO | claimed |