Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965169 | 0.94 | GPR119 (0.42) | GPR119S1PR1S1PR3DPP4DPP7 | |
| SCHEMBL17965062 | 0.89 | GPR119 (0.40) | GPR119DPP4DPP7KCNH2 | |
| SCHEMBL17964990 | 0.87 | GPR119 (0.42) | GPR119S1PR1S1PR3HDAC6KDM4E | |
| SCHEMBL17965042 | 0.87 | S1PR1 (0.40) | GPR119S1PR1S1PR3HDAC6DPP4 | |
| SCHEMBL17965205 | 0.87 | GPR119 (0.46) | GPR119S1PR1S1PR3HDAC6DPP4 | |
| SCHEMBL17965138 | 0.85 | GPR119 (0.42) | GPR119S1PR1S1PR3HDAC6DPP4 | |
| SCHEMBL17964986 | 0.85 | S1PR1 (0.43) | GPR119S1PR1S1PR3HDAC6KDM4E | |
| SCHEMBL17965170 | 0.84 | GPR119 (0.42) | GPR119DPP4DPP7KCNH2 | |
| SCHEMBL17965097 | 0.82 | GPR119 (0.39) | GPR119S1PR1S1PR3 | |
| SCHEMBL14707125 | 0.81 | GPR119 (0.46) | GPR119S1PR1S1PR3HDAC6DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |