Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 14/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965058 | 0.87 | GPR119 (0.43) | GPR119S1PR1S1PR3DRD3 | |
| SCHEMBL17965048 | 0.82 | GPR119 (0.42) | GPR119S1PR1S1PR3 | |
| SCHEMBL17964983 | 0.82 | S1PR1 (0.41) | GPR119S1PR1S1PR3 | |
| SCHEMBL17965107 | 0.81 | S1PR1 (0.41) | GPR119S1PR1S1PR3 | |
| SCHEMBL14694919 | 0.81 | S1PR1 (0.40) | S1PR1S1PR3DRD3 | |
| SCHEMBL17965169 | 0.81 | GPR119 (0.42) | GPR119S1PR1S1PR3 | |
| SCHEMBL14695355 | 0.81 | GPR119 (0.58) | GPR119 | |
| SCHEMBL17965062 | 0.79 | GPR119 (0.40) | GPR119 | |
| Trifluoroacetic Acid SCHEMBL14695494 | 0.78 | S1PR1 (0.38) | GPR119S1PR1S1PR3DRD3 | |
| SCHEMBL14707126 | 0.77 | GPR119 (0.58) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |