Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582222 | 0.85 | EPHX2 (0.45) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL25053381 | 0.85 | KDM1A (0.56) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL29952159 | 0.75 | PIM1 (0.44) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL29373513 | 0.73 | KDM1A (0.57) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL22086333 | 0.73 | KDM1A (0.57) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL29116029 | 0.73 | KDM1A (0.57) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL25053373 | 0.73 | KDM1A (0.57) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL17967133 | 0.72 | ALDH1A1 (0.41) | NPC1RAB9A | |
| SCHEMBL2629490 | 0.71 | EPHX2 (0.48) | EPHX2KDM1AMAOBBTKKMT2A | |
| SCHEMBL29878142 | 0.71 | EPHX2 (0.48) | EPHX2KDM1AMAOBBTKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016124938-A1 | AUTOTAXIN INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-08-11 | — | — | WO | disclosed |