Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970548 | 0.83 | KDM4A (0.41) | ALDH1A1 | |
| SCHEMBL17970371 | 0.72 | EZH2 (0.35) | — | |
| SCHEMBL17970532 | 0.71 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL17970581 | 0.69 | EZH2 (0.35) | ALDH1A1 | |
| SCHEMBL17970366 | 0.69 | EZH2 (0.35) | ALDH1A1LMNAHTT | |
| SCHEMBL17970530 | 0.67 | — | — | |
| SCHEMBL19903102 | 0.59 | TUBB4A (0.50) | ALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL7884826 | 0.59 | EZH2 (0.43) | — | |
| SCHEMBL19048549 | 0.58 | KDM4E (0.50) | ALDH1A1LMNA | |
| SCHEMBL30500734 | 0.58 | NOTUM (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773754-B1 | Compounds for use in the treatment of T-cell mediated diseases | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-08-03 | — | — | EP | disclosed |