Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.51 |
| ▸ | PRKDC | P78527 | 3/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | HCK | P08631 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 11/20 | 0.43 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467105 | 0.90 | JAK2 (0.46) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21467052 | 0.84 | KDR (0.48) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17970622 | 0.82 | KDR (0.44) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL129811 | 0.80 | PIK3CD (0.63) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL13826604 | 0.79 | LRRK2 (0.47) | PDPK1JAK3 | |
| SCHEMBL22275989 | 0.79 | MAP4K4 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL19414427 | 0.78 | PIK3CD (0.43) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3782102 | 0.78 | PIK3CD (0.57) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL21467079 | 0.78 | TGFBR1 (0.46) | KDRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30386858 | 0.76 | PIK3CD (0.61) | KDRPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| EP-3050876-A2 | KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2016-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | KDR 823/4885PIK3CD 103/4885PIK3CA 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.