SCHEMBL179730

SCHEMBL179730

Cc1ccccc1Nc1cccc2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 3/20 0.63
RHOA P61586 1/20 0.59
SNCA P37840 2/20 0.44
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
KMT2A Q03164 2/20 0.44
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
UBA2 Q9UBT2 1/20 0.44
CYP1A2 P05177 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31661371 1.00 CASP6 (0.63) CASP6RHOASNCAALDH1A1KDM4E
Potassium SCHEMBL7615456 0.99 CASP6 (0.61) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL2293946 0.89 CASP6 (0.49) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL25385245 0.87 CASP6 (0.50) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL7046526 0.83 CASP6 (0.62) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL31614400 0.82 SNCA (0.63) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL291102 0.82 SNCA (0.63) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL4303416 0.82 CASP6 (0.73) CASP6RHOASNCAALDH1A1KDM4E
SCHEMBL7037608 0.82 CASP6 (0.59) CASP6RHOASNCAALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL28873814 0.81 CASP6 (0.57) CASP6RHOASNCAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 500 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076072-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-12-13 US claimed
US-8026057-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-09-27 US claimed
US-7468243-B2 Nucleotide sequence labelling compoumd four use as tool in genetic engineering AFFYMETRIX, INC. (US) 2008-12-23 US claimed
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 US claimed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 US claimed
US-5298197-A Chemiluminescent microemulsions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-03-29 US claimed
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2025-05-13 US disclosed
US-20240384262-A1 LINKING SEQUENCE READS USING PAIRED CODE TAGS ILLUMINA, INC. 2024-11-21 US disclosed
US-11993772-B2 Linking sequence reads using paired code tags ILLUMINA, INC. (US) 2024-05-28 US disclosed
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. 2023-12-21 US disclosed
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2023-09-19 US disclosed
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE ILLUMINA, INC. (US) 2021-09-09 US disclosed
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2021-06-01 US disclosed
US-4256834-A REPRESSING THE SIGNALS PRODUCED BY UNBOUND LABELS; SENSITIVITY SYVA COMPANY (US) 1981-03-17 US disclosed
EP-0022768-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1981-01-28 EP disclosed
EP-0017908-A1 A method for determining the presence in a sample of an analyte and a kit for use in this method SYVA COMPANY (US) 1980-10-29 EP disclosed
EP-0015695-A1 Support-ligand analog-fluorescer conjugate and serum assay method involving such conjugate SYVA COMPANY (US) 1980-09-17 EP disclosed
EP-0022768-A4 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1980-08-18 EP disclosed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US disclosed
WO-1979000882-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA CO (US) 1979-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230406874-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 CASP6 4521/4885RHOA 1143/4885SNCA 2528/4885
US-11021504-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CASP6 4521/4885RHOA 1143/4885SNCA 2528/4885
US-20210277043-A1 FUNCTIONALIZATION AND PURIFICATION OF MOLECULES BY REVERSIBLE GROUP EXCHANGE PHAX, ALKBH1, JMJD6 CASP6 4521/4885RHOA 1143/4885SNCA 2528/4885
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CASP6 4521/4885RHOA 1143/4885SNCA 2528/4885
US-11760772-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 CASP6 4521/4885RHOA 1143/4885SNCA 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.