Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539082 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL28293945 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL79588 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL28294025 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL28099320 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL17612002 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TP53CYP3A4MAPK1 | |
| SCHEMBL4583431 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2TSHRTP53 | |
| SCHEMBL15234 | 0.78 | TSHR (0.47) | ALDH1A1SMN1; SMN2TSHRTP53CYP3A4 | |
| SCHEMBL1030890 | 0.78 | TSHR (0.47) | ALDH1A1SMN1; SMN2TSHRTP53CYP3A4 | |
| SCHEMBL17973516 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180222839-A1 | HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. | 2018-08-09 | — | — | US | disclosed |
| US-9938223-B2 | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions | SIRRUS, INC. (US) | 2018-04-10 | — | — | US | disclosed |
| US-9416091-B1 | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions | SIRRUS, INC. (US) | 2016-08-16 | — | — | US | disclosed |
| US-9416091-B1 | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions | SIRRUS, INC. (US) | 2016-08-16 | — | — | US | disclosed |
| US-20160229786-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229786-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160221922-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. | 2016-08-04 | — | — | US | disclosed |
| US-20160221922-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229786-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NOTUM, CES1, CYP4F11 | ALDH1A1 133/4885MAPT 3800/4885SMN1; SMN2 4819/4885 |
| US-20160221922-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NOTUM, CES1, CYP4F11 | ALDH1A1 133/4885MAPT 3800/4885SMN1; SMN2 4819/4885 |
| US-20180222839-A1 | HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NOTUM, CES1, ADH5 | ALDH1A1 137/4885MAPT 3780/4885SMN1; SMN2 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.