Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | HPGD | P15428 | 8/20 | 0.61 |
| ▸ | VDR | P11473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | CLTC | Q00610 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943446 | 0.81 | KDM4E (0.76) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL19985736 | 0.80 | KDM4E (0.85) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL19985734 | 0.78 | KDM4E (0.74) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL31108702 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL462047 | 0.78 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL19985729 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL19985731 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL19791321 | 0.74 | KDM4E (0.65) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL29532258 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1HPGDVDRMAPT | |
| SCHEMBL27006385 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1HPGDVDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9952508-B2 | Compounders for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2018-04-24 | — | — | US | disclosed |
| US-20160225611-A1 | COMPOUND FOR ENHANCING GENERATION OF CHEMICAL SPECIES | TOYO GOSEI CO., LTD. (JP) | 2016-08-04 | — | — | US | disclosed |