Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307827 | 0.88 | CYP2C19 (0.45) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL10307746 | 0.85 | MAPT (0.53) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL12808380 | 0.83 | ALDH1A1 (0.43) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| Cpi 613 SCHEMBL13333201 | 0.82 | CYP2C19 (0.59) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| Cpi 613 SCHEMBL1062218 | 0.82 | CYP2C19 (0.59) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL10454113 | 0.81 | CYP2C19 (0.46) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL17381514 | 0.81 | CYP2C19 (0.58) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL22299081 | 0.81 | CYP2C19 (0.58) | MAPTRXFP1HDAC3MAPK1ADRA1A | |
| SCHEMBL14027322 | 0.78 | ALDH1A1 (0.40) | MAPTRXFP1SMN1; SMN2CYP2C19IDO1 | |
| SCHEMBL10307822 | 0.78 | CYP2C19 (0.43) | MAPTRXFP1HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220678-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | RAFAEL PHARMACEUTICALS, INC. | 2016-08-04 | — | — | US | disclosed |
| US-20160220678-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | RAFAEL PHARMACEUTICALS, INC. | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220678-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING LIPOIC ACID DERIVATIVES | SLC25A1, SLC25A21, SLC25A11 | MAPT 2395/4885RXFP1 4531/4885HDAC3 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.