Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974087 | 0.99 | PRMT1 (0.43) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL14300898 | 0.87 | FOLH1 (0.44) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL14597382 | 0.83 | PRMT1 (0.55) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL8958768 | 0.83 | PRMT1 (0.41) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL12713670 | 0.83 | FOLH1 (0.48) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL16000425 | 0.81 | FOLH1 (0.46) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL14556407 | 0.81 | FOLH1 (0.46) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL25862256 | 0.81 | PRMT1 (0.51) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL12415021 | 0.81 | PRMT1 (0.56) | PRMT1PRMT5CARM1PRMT8FOLH1 | |
| SCHEMBL12832513 | 0.81 | PRMT1 (0.56) | PRMT1PRMT5CARM1PRMT8FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220704-A1 | PYRIDAZINOINDOLE COMPOUNDS AND METHODS FOR PET IMAGING | VANDERBILT UNIVERSITY | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220704-A1 | PYRIDAZINOINDOLE COMPOUNDS AND METHODS FOR PET IMAGING | TSPO, SLC25A17, SLC19A2 | PRMT1 4195/4885PRMT5 3293/4885CARM1 4571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.