Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17976343 | 0.99 | ALDH1A1 (0.44) | LMNAKMT2AALDH1A1MAPTGAA | |
| SCHEMBL18006541 | 0.99 | ALDH1A1 (0.44) | LMNAKMT2AALDH1A1MAPTGAA | |
| SCHEMBL17976303 | 0.93 | ALK (0.47) | KMT2AALDH1A1MAPTGAAHPGD | |
| SCHEMBL17975959 | 0.92 | MAPK1 (0.54) | LMNAKMT2AMAPTSMN1; SMN2HIF1A | |
| SCHEMBL7982079 | 0.92 | ALDH1A1 (0.51) | LMNAKMT2AALDH1A1MAPTGAA | |
| SCHEMBL17976095 | 0.91 | HIF1A (0.44) | LMNAKMT2AALDH1A1GAAHPGD | |
| SCHEMBL17976097 | 0.91 | HIF1A (0.44) | LMNAKMT2AALDH1A1GAAHPGD | |
| SCHEMBL3161761 | 0.91 | KMT2A (0.52) | LMNAKMT2AALDH1A1MAPTGAA | |
| SCHEMBL3161752 | 0.91 | KMT2A (0.52) | LMNAKMT2AALDH1A1MAPTGAA | |
| SCHEMBL17976020 | 0.90 | DYRK1A (0.45) | LMNAKMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016131789-A1 | BENZOPYRROLIDONE DERIVATIVES POSSESSING ANTIVIRAL AND ANTICANCER PROPERTIES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-08-25 | — | — | WO | disclosed |
| EP-3056202-A1 | BENZOPYRROLIDONE DERIVATIVES POSSESSING ANTIVIRAL AND ANTICANCER PROPERTIES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-08-17 | — | — | EP | disclosed |