Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350172 | 0.88 | L3MBTL1 (0.68) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL30556174 | 0.87 | L3MBTL1 (0.76) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL25009812 | 0.87 | L3MBTL1 (0.76) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL14741028 | 0.85 | LMNA (0.66) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL28833898 | 0.85 | LMNA (0.74) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL10911030 | 0.85 | L3MBTL1 (0.73) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL31259739 | 0.85 | L3MBTL1 (0.73) | KMT2ALMNATDP1L3MBTL1MAPT | |
| Ethyl Nicotinate SCHEMBL9679078 | 0.84 | L3MBTL1 (0.68) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL28174527 | 0.84 | LMNA (0.76) | KMT2ALMNATDP1L3MBTL1MAPT | |
| SCHEMBL28174523 | 0.84 | LMNA (0.76) | KMT2ALMNATDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024022332-A1 | FAP INHIBITORS | SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) | 2024-02-01 | — | — | WO | disclosed |
| WO-2022253252-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS | SILEXON BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| CN-109952297-B | Compound (I) | 奥斯陆大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-108137518-B | 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2021-08-31 | — | — | CN | disclosed |
| CN-109153643-A | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2019-01-04 | — | — | CN | disclosed |
| WO-2018157277-A1 | ISOQUINOLIN AND NAPHTHYDRIN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2018-09-07 | — | — | WO | disclosed |
| EP-3256468-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-12-20 | — | — | EP | disclosed |
| CN-105899509-A | Isopropyl triazolopyridine compounds | 伊莱利利公司 | 2016-08-24 | — | — | CN | disclosed |
| WO-2016127924-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |
| CN-101589025-B | Aminonicotinic acid and isonicotinic acid derivatives as dihydrolactate dehydrogenase (DHODH) inhibitors | ALMIRALL LAB | 2012-05-30 | — | — | CN | disclosed |
| CN-101589025-A | Aminonicotinic acid and isonicotinic acid derivatives as dihydrolactate dehydrogenase (DHODH) inhibitors | ALMIRALL LAB (ES) | 2009-11-25 | — | — | CN | disclosed |