Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17978271 | 0.99 | HTR1A (0.53) | HTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL17978326 | 0.93 | HTR1A (0.52) | HTR1ASLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL17978324 | 0.92 | HTR1A (0.52) | HTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1885658 | 0.83 | GRIN2B (0.54) | HTR1A | |
| SCHEMBL29881785 | 0.83 | GRIN2B (0.54) | HTR1A | |
| SCHEMBL28246553 | 0.80 | S1PR1 (0.53) | — | |
| SCHEMBL12173611 | 0.80 | SLC6A2 (0.61) | HTR1ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1889871 | 0.78 | PIM1 (0.50) | HTR1ASLC6A2SLC6A3SLC6A4 | |
| Chloromethane SCHEMBL15205595 | 0.78 | PIM1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL15206544 | 0.77 | PIM1 (0.49) | HTR1ASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128987-A1 | A PROCESS FOR PREPARATION OF 2-BENZOFURANCARBOXAMIDE, 5-[4-[4-(5CYANO-1H-INDOL-3-YL)BUTYL]-1-PIPERAZINYL] FREE BASE AND ITS HYDROCHLORIDE SALT | HARMAN FINOCHEM LIMITED (IN) | 2016-08-18 | — | — | WO | disclosed |