Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | DGKG | P49619 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MPO | P05164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diacylglycerol Kinase Inhibitor Ii SCHEMBL317664 | 0.81 | MAPT (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| SCHEMBL2730275 | 0.74 | ALDH1A1 (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Altanserin SCHEMBL30136526 | 0.74 | HTR2A (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Altanserin SCHEMBL12629110 | 0.74 | HTR2A (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Altanserin SCHEMBL30136524 | 0.74 | HTR2A (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Altanserin SCHEMBL404849 | 0.74 | HTR2A (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Altanserin SCHEMBL15662949 | 0.73 | HTR2A (1.00) | MAPTDGKADGKGHIF1AHTR2A | |
| Hydrochloric Acid SCHEMBL2730111 | 0.73 | ALDH1A1 (0.97) | MAPTDGKADGKGHIF1AHTR2A | |
| SCHEMBL2732924 | 0.73 | KMT2A (1.00) | MAPTDGKADGKGHIF1AHPGD | |
| Hydrochloric Acid SCHEMBL2731304 | 0.72 | KMT2A (0.97) | MAPTDGKADGKGHIF1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127255-A1 | MEDIATION OF INFLAMMATORY RESPONSE USING INHIBITORS OF NETOSIS | NADESALINGAM PALANIYAR (CA) | 2016-08-18 | — | — | WO | disclosed |