Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043777 | 0.89 | LMNA (0.50) | LMNATRIM24TP53MAPTMEN1 | |
| SCHEMBL21043862 | 0.88 | LMNA (0.52) | LMNATP53MAPTMEN1ALDH1A1 | |
| SCHEMBL19865877 | 0.85 | HDAC1 (0.41) | LMNATP53POLBTMEM97CHRM1 | |
| SCHEMBL17979403 | 0.82 | LMNA (0.48) | LMNATRIM24TP53MAPTMEN1 | |
| SCHEMBL17979556 | 0.82 | POLB (0.43) | LMNATHRBKMT2APOLBCHRM1 | |
| SCHEMBL17979478 | 0.81 | LMNA (0.49) | LMNATP53MAPTMEN1ALDH1A1 | |
| SCHEMBL17979546 | 0.81 | LMNA (0.47) | LMNATP53MAPTMEN1ALDH1A1 | |
| SCHEMBL21043782 | 0.81 | CYP19A1 (0.52) | LMNAMAPTMEN1ALDH1A1THRB | |
| SCHEMBL21043885 | 0.80 | CYP19A1 (0.54) | LMNAMAPTMEN1ALDH1A1THRB | |
| SCHEMBL21043855 | 0.79 | MAPT (0.52) | LMNATP53MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |