Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043782 | 0.92 | CYP19A1 (0.52) | CYP19A1LMNAMAPTALDH1A1TSHR | |
| SCHEMBL21043802 | 0.88 | MAPT (0.53) | CYP19A1LMNAMAPTALDH1A1THRB | |
| SCHEMBL21043884 | 0.87 | CYP19A1 (0.50) | CYP19A1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL21043790 | 0.87 | POLB (0.61) | CYP19A1LMNAMAPTSMN1; SMN2USP2 | |
| SCHEMBL21043862 | 0.87 | LMNA (0.52) | LMNAMAPTALDH1A1THRBRECQL | |
| SCHEMBL21043825 | 0.85 | CYP19A1 (0.54) | CYP19A1LMNAMAPTPOLBATAD2 | |
| SCHEMBL21043838 | 0.81 | TP53 (0.47) | LMNAMAPTALDH1A1THRBRECQL | |
| SCHEMBL21043831 | 0.81 | ATAD2 (0.46) | LMNAMAPTTHRBPOLBATAD2 | |
| SCHEMBL17979487 | 0.80 | LMNA (0.48) | LMNAMAPTALDH1A1THRBRECQL | |
| SCHEMBL21043855 | 0.80 | MAPT (0.52) | CYP19A1LMNAMAPTALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |