SCHEMBL17980366

SCHEMBL17980366

CC1CC1Nc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 5/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.40
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 2/20 0.38
ALOX12 P18054 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
RAD52 P43351 1/20 0.38
GFER P55789 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13281999 0.87 FUCA1 (0.41) FUCA1ALDH1A1MEN1MAPTKMT2A
SCHEMBL4972989 0.82 CARM1 (0.40) ALDH1A1NFKB1NFKB2RELAMEN1
SCHEMBL27831554 0.80 KDM1A (0.44) ALDH1A1TSHRMEN1MAPTKMT2A
SCHEMBL7634555 0.79 ALDH1A1 (0.51) ALDH1A1TSHRSMN1; SMN2LMNAGFER
SCHEMBL9618129 0.78 ALDH1A1 (0.35) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL6266941 0.77 KDM1A (0.42) FUCA1ALDH1A1GFERHTR2BCARM1
SCHEMBL23848517 0.77 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDLMNAGFER
SCHEMBL5766184 0.77 SSTR1 (0.39) ALDH1A1TSHRNFKB1NFKB2RELA
SCHEMBL29127174 0.77 NPSR1 (0.47) ALDH1A1MEN1MAPTKMT2ASMN1; SMN2
SCHEMBL29127134 0.76 ALDH1A1 (0.41) ALDH1A1TSHRNFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143007-A Tetrahydrocarbazole derivative and photocatalytic synthesis method thereof 陕西科技大学 2023-12-01 CN claimed
US-20250287942-A1 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-18 US disclosed
CN-117143007-A Tetrahydrocarbazole derivative and photocatalytic synthesis method thereof 陕西科技大学 2023-12-01 CN disclosed
WO-2023205458-A2 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-26 WO disclosed
EP-3256448-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS Bayer CropScience Aktiengesellschaft (DE) 2017-12-20 EP disclosed
WO-2016128365-A1 SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250287942-A1 FORMULATIONS FOR REPELLING BEES AND OTHER INSECTS ACHE, BCHE, DDT FUCA1 4369/4885ALDH1A1 4134/4885TSHR 4454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.