SCHEMBL17980418

SCHEMBL17980418

CCCCCCCCCCCCCCC(=O)C(=O)OCCCC(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.61
PPARG P37231 7/20 0.61
PPARD Q03181 7/20 0.61
PPARA Q07869 7/20 0.61
HDAC11 Q96DB2 5/20 0.61
TSHR P16473 4/20 0.61
PTPN1 P18031 3/20 0.61
ALDH1A1 P00352 2/20 0.61
TLR2 O60603 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
FABP4 P15090 2/20 0.61
KMT2A Q03164 2/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
SLC22A8 Q8TCC7 1/20 0.61
MEN1 O00255 1/20 0.61
ESR1 P03372 1/20 0.61
ALOX15 P16050 1/20 0.61
PDE4A P27815 1/20 0.61
PDE3A Q14432 1/20 0.61
HSD17B10 Q99714 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17980377 0.96 GPR84 (0.61) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL7752967 0.93 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL29747328 0.89 AKR1B1 (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL10882394 0.89 FAAH (0.61) TSHRFAAHCES2CES1
SCHEMBL8167954 0.89 FAAH (0.61) GPR84PPARGPPARDPPARATSHR
SCHEMBL9340088 0.89 FAAH (0.61) GPR84PPARGPPARDPPARATSHR
SCHEMBL9002350 0.89 FAAH (0.61) TSHRFAAHCES2CES1
SCHEMBL9002877 0.89 FAAH (0.61) TSHRFAAHCES2CES1
SCHEMBL4160109 0.87 TSHR (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4157138 0.87 TSHR (0.55) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016128132-A1 2-OXOESTER COMPOUNDS AND USES THEREOF NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) 2016-08-18 WO claimed
WO-2016128132-A1 2-OXOESTER COMPOUNDS AND USES THEREOF NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) 2016-08-18 WO disclosed