Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17980410 | 0.97 | DGKA (0.50) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL30842929 | 0.87 | DGKA (0.67) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL30842970 | 0.87 | DGKA (0.67) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL30842927 | 0.87 | DGKA (0.67) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL30842923 | 0.87 | DGKA (0.67) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL16012871 | 0.86 | DGKA (0.55) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL10882394 | 0.85 | FAAH (0.61) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL9002877 | 0.85 | FAAH (0.61) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL9002350 | 0.85 | FAAH (0.61) | DGKAFAAHTSHRNAAAPRSS1 | |
| SCHEMBL30804536 | 0.85 | FAAH (0.61) | DGKAFAAHTSHRNAAAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128132-A1 | 2-OXOESTER COMPOUNDS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-08-18 | — | — | WO | disclosed |
| WO-2016128132-A1 | 2-OXOESTER COMPOUNDS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2016-08-18 | — | — | WO | disclosed |