Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16588235 | 0.88 | THRB (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL107954 | 0.84 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.83 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5144090 | 0.83 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25426 | 0.83 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2720435 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16309330 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8748019 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| Hydrochloric Acid SCHEMBL6053163 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12651026 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111870-A | PRIMER COMPOSITION OF AN ACRYLIC EPOXY ESTER GRAFT COPOLYMER, A HIGH MOLECULAR WEIGHT EPOXY RESIN AND A HEAT REACTIVE CONDENSATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-7951429-B2 | High energy curable coatings comprising thermoplastic polymers | THE SHERWIN-WILLIAMS COMPANY (US) | 2011-05-31 | — | — | US | disclosed |
| US-20090214877-A1 | HIGH ENERGY CURABLE COATINGS COMPRISING THERMOPLASTIC POLYMERS | THE SHERWIN-WILLIAMS COMPANY (US) | 2009-08-27 | — | — | US | disclosed |
| US-7527864-B2 | High energy curable coatings comprising thermoplastic polymers | THE SHERWIN-WILLIAMS COMPANY (US) | 2009-05-05 | — | — | US | disclosed |
| US-20050209358-A1 | High energy curable coatings comprising thermoplastic polymers | SHERWIN-WILLIAMS COMPANY THE | 2005-09-22 | — | — | US | disclosed |
| US-4111870-A | PRIMER COMPOSITION OF AN ACRYLIC EPOXY ESTER GRAFT COPOLYMER, A HIGH MOLECULAR WEIGHT EPOXY RESIN AND A HEAT REACTIVE CONDENSATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-09-05 | — | — | US | disclosed |