Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.32 |
| ▸ | F10 | P00742 | 11/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800884 | 0.92 | F2 (0.32) | F2F10PRSS1CA1CA2 | |
| SCHEMBL1801804 | 0.89 | PDK2 (0.34) | F2F10PRSS1KDM4EALDH1A1 | |
| SCHEMBL1797793 | 0.88 | KDM4E (0.33) | F2F10PRSS1KDM4ECA1 | |
| SCHEMBL1801082 | 0.88 | ACLY (0.33) | F2F10PRSS1KDM4EALDH1A1 | |
| SCHEMBL1797708 | 0.87 | ACVR1 (0.37) | F2F10PRSS1KDM4EALDH1A1 | |
| SCHEMBL1798500 | 0.85 | SMN1; SMN2 (0.32) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL1795782 | 0.85 | F2 (0.32) | F2F10PRSS1LMNAMAPT | |
| SCHEMBL1795743 | 0.82 | CA1 (0.36) | F2F10PRSS1KDM4EALDH1A1 | |
| SCHEMBL1799389 | 0.82 | NPC1 (0.36) | F2F10PRSS1KDM4EMAPT | |
| SCHEMBL1466563 | 0.81 | NOTUM (0.34) | F2F10PRSS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135496-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-05-15 | — | — | US | disclosed |
| US-8673951-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20110144334-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7951828-B1 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144334-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | OR10J3, OR51E2, ORMDL3 | F2 2442/4885F10 2303/4885PRSS1 4137/4885 |
| US-20140135496-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | OR10J3, OR51E2, ODC1 | F2 2600/4885F10 3137/4885PRSS1 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.