Ethylene Glycol

Ethylene Glycol

SCHEMBL17985187

O=C(O)c1ccc(C(=O)O)c2c1CC1CCCCC1C2.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.37
CYP1A2 P05177 1/20 0.35
KDM4C Q9H3R0 2/20 0.34
NR3C2 P08235 2/20 0.33
ACLY P53396 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ASPH Q12797 1/20 0.33
KDM8 Q8N371 1/20 0.33
GAA P10253 1/20 0.32
ABCC1 P33527 1/20 0.32
KDM6B O15054 1/20 0.32
KDM4A O75164 1/20 0.32
KDM4D Q6B0I6 1/20 0.32
KDM3B Q7LBC6 1/20 0.32
HIF1AN Q9NWT6 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
KMT2A Q03164 1/20 0.32
CAMKK1 Q8N5S9 1/20 0.32
CAMKK2 Q96RR4 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667757 0.93 CYP1A2 (0.41) ACMSDCYP1A2KDM4CNR3C2ALDH1A1
SCHEMBL17295966 0.85 NR3C2 (0.33) ACMSDNR3C2ALDH1A1KDM4E
Ethylene Glycol SCHEMBL3016260 0.81 CYP1A2 (0.38) ACMSDCYP1A2KDM4CALDH1A1KMT2A
SCHEMBL6432329 0.77 CYP1A2 (0.44) ACMSDCYP1A2ALDH1A1GAAKDM4E
Ethylene Glycol SCHEMBL1325969 0.74 CYP1A2 (0.52) CYP1A2ALDH1A1GAAKMT2AKDM4E
SCHEMBL370115 0.72 CYP1A2 (0.44) ACMSDCYP1A2ALDH1A1GAAKMT2A
SCHEMBL28837884 0.72 CYP1A2 (0.64) ACMSDCYP1A2KDM4CALDH1A1ABCC1
SCHEMBL7697258 0.70 CYP1A2 (0.39) ACMSDCYP1A2KDM4CALDH1A1KDM4E
Ethylene Glycol SCHEMBL1924197 0.70 CYP1A2 (0.34) CYP1A2ALDH1A1KDM4ENPC1RAB9A
SCHEMBL4916533 0.69 CYP1A2 (0.44) CYP1A2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160236443-A1 OPTICALLY TRANSPARENT COMPOSITE FILM FOR DISPLAY AND MANUFACTURING METHOD THEREFOR ICOMPONENTS CO., LTD. (KR) 2016-08-18 US claimed
US-20160236443-A1 OPTICALLY TRANSPARENT COMPOSITE FILM FOR DISPLAY AND MANUFACTURING METHOD THEREFOR ICOMPONENTS CO., LTD. (KR) 2016-08-18 US disclosed