SCHEMBL667757

SCHEMBL667757

O=C(O)c1ccc(C(=O)O)c2c1CC1CCCCC1C2

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
ACMSD Q8TDX5 2/20 0.41
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
ABCC1 P33527 2/20 0.35
GAA P10253 1/20 0.35
NR3C2 P08235 1/20 0.34
SELL P14151 1/20 0.34
SELP P16109 1/20 0.34
SRD5A2 P31213 1/20 0.34
KDM4C Q9H3R0 2/20 0.34
MAPK1 P28482 1/20 0.34
CAMKK2 Q96RR4 2/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CAMKK1 Q8N5S9 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL17985187 0.93 ACMSD (0.37) CYP1A2ACMSDALDH1A1ABCC1GAA
SCHEMBL6432329 0.83 CYP1A2 (0.44) CYP1A2ACMSDALDH1A1ALOX15GAA
SCHEMBL17295966 0.82 NR3C2 (0.33) ACMSDALDH1A1NR3C2MAPK1TSHR
SCHEMBL28837884 0.78 CYP1A2 (0.64) CYP1A2ACMSDALDH1A1ALOX15ABCC1
SCHEMBL370115 0.78 CYP1A2 (0.44) CYP1A2ACMSDALDH1A1ALOX15GAA
SCHEMBL4916533 0.74 CYP1A2 (0.44) CYP1A2ALDH1A1ALOX15SELLSELP
SCHEMBL6681994 0.73 ACMSD (0.34) CYP1A2ACMSDALDH1A1ALOX15ABCC1
Biphenyl SCHEMBL8525491 0.72 ALDH1A1 (0.61) ACMSDALDH1A1ALOX15ABCC1GAA
SCHEMBL7944589 0.72 CYP1A2 (0.43) CYP1A2ACMSDALDH1A1ALOX15GAA
Ethylene Glycol SCHEMBL3016260 0.72 CYP1A2 (0.38) CYP1A2ACMSDALDH1A1ALOX15SELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3655477-B1 POLYMER COMPOSITIONS COMPRISING CRYSTALLINE POLYMERS AND A STABILIZER COMPOSITION EASTMAN CHEM CO (US) 2023-10-25 EP claimed
EP-2708214-B1 Device for carrying out therapeutic and/or cosmetic treatment of warts or similar tissue abnormalities raised from the surface of the skin of a living being ZALZADEH ARIO (DE) 2017-11-29 EP claimed
US-9452061-B2 Spinal fusion cage DSM IP ASSETS B.V. (NL) 2016-09-27 US claimed
US-9228080-B2 Reinforced PCT compositions TICONA LLC (US) 2016-01-05 US claimed
US-20140045978-A1 Reinforced PCT Compositions TICONA LLC (US) 2014-02-13 US claimed
US-8557910-B2 Reinforced PCT compositions TICONA LLC 2013-10-15 US claimed
EP-2307498-B1 LONG-TERM HEAT AGING RESISTANT IMPACT MODIFIED POLY(CYCLOHEXYLENE-DIMETHYLENE) TEREPHTHALATE COMPOSITIONS TICONA LLC (US) 2013-09-11 EP claimed
US-8361577-B2 Long-term heat aging resistant impact modified poly(cyclohexylene-dimethylene) terephthalate compositions TICONA LLC (US) 2013-01-29 US claimed
JP-2011529978-A 2011-12-15 JP claimed
EP-2307498-A1 LONG-TERM HEAT AGING RESISTANT IMPACT MODIFIED POLY(CYCLOHEXYLENE-DIMETHYLENE) TEREPHTHALATE COMPOSITIONS Ticona LLC (US) 2011-04-13 EP claimed
EP-2092012-B1 REINFORCED PCT COMPOSITIONS DU PONT (US) 2010-09-15 EP claimed
WO-2010014475-A1 LONG-TERM HEAT AGING RESISTANT IMPACT MODIFIED POLY(CYCLOHEXYLENE-DIMETHYLENE) TEREPHTHALATE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
US-20100028579-A1 Long-Term heat Aging Resistant Impact Modified Poly(cyclohexylene-dimethylene) Terephthalate Compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20090043033-A1 Reinforced polyester compositions for high dielectric performance E. I. DU PONT DE NEMOURS AND COMPANY 2009-02-12 US claimed
EP-1420840-B1 FASTENING DEVICE FOR INJECTION NEEDLES TECPHARMA LICENSING AG (CH) 2006-12-27 EP claimed
US-20050221159-A1 Liquid fuel cell KABUSHIKI KAISHA TOSHIBA (JP) 2005-10-06 US claimed
EP-0393616-B1 Thermoplastic polyester resin composition MITSUBISHI RAYON CO (JP) 1994-12-21 EP claimed
EP-0445342-B1 Colored cosmetic compositions ESTEE LAUDER INC (US) 1994-01-26 EP claimed
WO-1989010989-A1 BICOMPONENT SYNTHETIC FIBRE AND PROCESS FOR PRODUCING SAME DANAKLON A/S (DK) 1989-11-16 WO claimed
EP-0340763-A1 Bicomponent synthetic fibre and process for producing same DANAKLON A/S (DK) 1989-11-08 EP claimed