Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126397 | 0.86 | DRD2 (0.41) | HTR2AHTR2CHTR2BDRD2ACACB | |
| SCHEMBL4126395 | 0.86 | DRD2 (0.41) | HTR2AHTR2CHTR2BDRD2ACACB | |
| SCHEMBL4134674 | 0.86 | HTR2C (0.50) | HTR2AHTR2CHTR2BDRD2ACACB | |
| SCHEMBL4134676 | 0.86 | HTR2C (0.50) | HTR2AHTR2CHTR2BDRD2ACACB | |
| SCHEMBL13742044 | 0.85 | ACACB (0.43) | DRD2ACACBMTNR1BACACAIDO1 | |
| SCHEMBL13742538 | 0.85 | MTNR1B (0.41) | DRD2ACACBMTNR1BACACAIDO1 | |
| SCHEMBL14797776 | 0.85 | NQO2 (0.41) | HTR2AHTR2CDRD2ACACBACACA | |
| SCHEMBL14797777 | 0.85 | NQO2 (0.41) | HTR2AHTR2CDRD2ACACBACACA | |
| SCHEMBL14802708 | 0.84 | SERPINE1 (0.38) | HTR2AHTR2CHTR2BDRD2ACACB | |
| SCHEMBL23544489 | 0.83 | IDO1 (0.40) | HTR2AHTR2CHTR2BDRD2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016123164-A1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-08-04 | — | — | WO | disclosed |