Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23544489 | 1.00 | IDO1 (0.40) | IDO1HTR2CALDH1A1HPGDHTT | |
| SCHEMBL17986628 | 0.88 | SERPINE1 (0.39) | IDO1HTR2CALDH1A1HPGDHTT | |
| SCHEMBL14797777 | 0.88 | NQO2 (0.41) | HTR2CALDH1A1HPGDKDM4EACACB | |
| SCHEMBL21335602 | 0.88 | SERPINE1 (0.39) | IDO1HTR2CALDH1A1HPGDHTT | |
| SCHEMBL14797776 | 0.88 | NQO2 (0.41) | HTR2CALDH1A1HPGDKDM4EACACB | |
| SCHEMBL14802708 | 0.87 | SERPINE1 (0.38) | HTR2CALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL14802654 | 0.86 | HTR2C (0.44) | HTR2CHTR2BHTR2ASERPINE1 | |
| SCHEMBL17986378 | 0.84 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL17986302 | 0.84 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL17985446 | 0.83 | HTR2A (0.50) | IDO1HTR2CACACBACACADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250549-B1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | UNIV ILLINOIS (US) | 2021-06-23 | — | — | EP | disclosed |
| US-10407381-B2 | Cyclopropylmethanamines as selective 5-HT(2C) receptor agonists | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-09-10 | — | — | US | disclosed |
| WO-2016123164-A1 | CYCLOPROPYLMETHANAMINES AS SELECTIVE 5-HT(2C) RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407381-B2 | Cyclopropylmethanamines as selective 5-HT(2C) receptor agonists | HTR2C, HTR2A, HTR1A | IDO1 375/4885HTR2C 1/4885ALDH1A1 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.