Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798621 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GLP1RGCGRMDM2MEN1 | |
| SCHEMBL3831391 | 0.78 | HDAC6 (0.45) | ALDH1A1MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL1800282 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GLP1RGCGRMEN1KMT2A | |
| SCHEMBL1800409 | 0.76 | ALDH1A1 (0.41) | ALDH1A1GLP1RGCGRMDM2MEN1 | |
| SCHEMBL2065633 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL3326164 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL25132126 | 0.69 | ALDH1A1 (0.39) | ALDH1A1GLP1RGCGRMEN1KMT2A | |
| SCHEMBL2924337 | 0.69 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AATMRAB9A | |
| SCHEMBL23682590 | 0.68 | ALDH1A1 (0.38) | ALDH1A1GLP1RGCGRMEN1KMT2A | |
| SCHEMBL15010610 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951951-B2 | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-31 | — | — | US | disclosed |