Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22731801 | 0.87 | CTSC (0.39) | FOLH1BLMTSHRKMT2ACYP2D6 | |
| SCHEMBL29768848 | 0.87 | CTSC (0.39) | FOLH1BLMTSHRKMT2ACYP2D6 | |
| SCHEMBL16181956 | 0.87 | CTSC (0.39) | FOLH1BLMTSHRKMT2ACYP2D6 | |
| SCHEMBL24486692 | 0.84 | PLA2G2C (0.42) | FOLH1TSHRNFKB1RIMKLANAALAD2 | |
| SCHEMBL173035 | 0.84 | PLA2G2C (0.42) | FOLH1TSHRNFKB1RIMKLANAALAD2 | |
| SCHEMBL24798437 | 0.83 | FOLH1 (0.33) | FOLH1BLMTSHRKMT2ACYP2D6 | |
| SCHEMBL12664911 | 0.82 | PLA2G2C (0.49) | FOLH1TSHRKMT2ANFKB1MEN1 | |
| SCHEMBL12324725 | 0.82 | PLA2G2C (0.45) | FOLH1RIMKLANAALAD2GABRPGABRD | |
| SCHEMBL12324731 | 0.80 | PLA2G2C (0.39) | FOLH1RIMKLANAALAD2GABRPGABRD | |
| SCHEMBL3791704 | 0.79 | LMNA (0.52) | FOLH1BLMTSHRKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | SLC7A1, SLC47A1, SLC47A2 | FOLH1 51/4885BLM 4560/4885TSHR 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.