SCHEMBL17986705

SCHEMBL17986705

BrCc1c(CBr)c(CBr)c2ccccc2c1CBr

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 2/20 0.43
TRPA1 O75762 1/20 0.43
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TNNI3 P19429 1/20 0.34
TNNT2 P45379 1/20 0.34
TNNC1 P63316 1/20 0.34
PLK1 P53350 1/20 0.34
HSD17B10 Q99714 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 2/20 0.33
HTR2A P28223 1/20 0.33
ELANE P08246 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PTPN1 P18031 1/20 0.32
CYP1A2 P05177 4/20 0.32
CYP2C19 P33261 2/20 0.32
IDO1 P14902 1/20 0.32
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11826109 0.94 ALDH1A1 (0.43) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL1719724 0.90 ALDH1A1 (0.45) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL29791960 0.90 ALDH1A1 (0.45) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL11828551 0.82 L3MBTL1 (0.46) ALDH1A1TSHRTRPA1KMT2APLK1
SCHEMBL13815223 0.80 ALDH1A1 (0.38) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL797164 0.80 KDM4E (0.50) ALDH1A1TSHRPLK1ELANECYP1A2
SCHEMBL12527459 0.78 CYP3A4 (0.46) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL12495279 0.73 ALDH1A1 (0.47) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL20312982 0.73 MEN1 (0.40) ALDH1A1TSHRTRPA1MEN1KMT2A
SCHEMBL29516177 0.73 HTR2A (0.60) ALDH1A1TSHRMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105940304-B The detection of the cleavage activity of enzyme 莫罗吉有限公司 2019-09-13 CN claimed
US-12320804-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2025-06-03 US disclosed
US-20250157661-A1 MONITORING INFLAMMATION STATUS MOLOGIC LIMITED (GB) 2025-05-15 US disclosed
US-11953506-B2 Monitoring inflammation status MOLOGIC LIMITED (GB) 2024-04-09 US disclosed
EP-3928100-B1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LTD (GB) 2023-03-22 EP disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
US-20220120760-A1 TREATMENT STRATIFICATION FOR AN EXACERBATION OF INFLAMMATION MOLOGIC LIMITED (GB) 2022-04-21 US disclosed
US-10866236-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2020-12-15 US disclosed
US-10866236-B2 Detection of cleavage activity of an enzyme MOLOGIC LIMITED (GB) 2020-12-15 US disclosed
US-20200378963-A1 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LIMITED (GB) 2020-12-03 US disclosed
CN-106255885-B Monitoring inflammatory states 莫洛迪克有限公司 2019-09-10 CN disclosed
EP-3111226-B1 MONITORING INFLAMMATION STATUS MOLOGIC LTD (GB) 2019-05-01 EP disclosed
EP-3111226-B1 MONITORING INFLAMMATION STATUS MOLOGIC LTD (GB) 2019-05-01 EP disclosed
EP-3060915-B1 DETECTION OF CLEAVAGE ACTIVITY OF AN ENZYME MOLOGIC LTD (GB) 2018-12-05 EP disclosed
US-20170108511-A1 Monitoring Inflammation Status MOLOGIC LIMITED (GB) 2017-04-20 US disclosed
US-20170108511-A1 Monitoring Inflammation Status MOLOGIC LIMITED (GB) 2017-04-20 US disclosed
CN-106255885-A Monitoring inflammatory states 莫洛迪克有限公司 2016-12-21 CN disclosed
CN-105940304-A Detection of cleavage activity of an enzyme 莫罗吉有限公司 2016-09-14 CN disclosed
US-20160238596-A1 Detection of Cleavage Activity Of An Enzyme MOLOGIC LIMITED (GB) 2016-08-18 US disclosed
US-20160238596-A1 Detection of Cleavage Activity Of An Enzyme MOLOGIC LIMITED (GB) 2016-08-18 US disclosed