Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986866 | 0.86 | L3MBTL1 (0.43) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15549030 | 0.82 | L3MBTL1 (0.50) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL17962541 | 0.82 | L3MBTL1 (0.50) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL17986802 | 0.82 | L3MBTL1 (0.50) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25793189 | 0.75 | L3MBTL1 (0.51) | L3MBTL1LMNACYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL26790644 | 0.73 | L3MBTL1 (0.61) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3168186 | 0.71 | DGAT1 (0.58) | L3MBTL1ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL3168169 | 0.71 | DGAT1 (0.58) | L3MBTL1ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL7479934 | 0.71 | L3MBTL1 (0.57) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL17986804 | 0.71 | L3MBTL1 (0.47) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016119707-A1 | NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-08-04 | — | — | WO | disclosed |