Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17973930 | 0.84 | ALDH1A1 (0.47) | ALDH1A1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL28529722 | 0.84 | ESR1 (0.50) | ESR1ESR2ACACBCXCR1CXCR2 | |
| SCHEMBL5766030 | 0.83 | ALDH1A1 (0.53) | ALDH1A1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL16577978 | 0.83 | SRC (0.48) | ESR1ESR2ACACBATMCXCR1 | |
| SCHEMBL3309903 | 0.82 | ESR1 (0.49) | ESR1ESR2ACACBKMT2AMIF | |
| SCHEMBL7904948 | 0.81 | ALDH1A1 (0.51) | ALDH1A1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL8406161 | 0.80 | ESR1 (0.58) | ALDH1A1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL31579489 | 0.77 | LTA4H (0.60) | ALDH1A1ACACBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10185057 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ESR1ESR2KMT2AMEN1 | |
| SCHEMBL6839674 | 0.76 | ALDH1A1 (0.51) | ALDH1A1ESR1KMT2AMEN1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220689-A1 | MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES | STARPHARMA PTY LTD. (AU) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220689-A1 | MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES | CD44, FOLR1, FOLH1 | ALDH1A1 610/4885ESR1 4002/4885ESR2 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.