Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.64 |
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | CA9 | Q16790 | 5/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974332 | 0.87 | CA12 (0.66) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL17974334 | 0.87 | CA12 (0.66) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL3683825 | 0.86 | CA12 (0.64) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL18226889 | 0.86 | CA12 (0.68) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL13907700 | 0.85 | ALDH1A1 (0.68) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL926118 | 0.85 | CA12 (0.63) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL15391900 | 0.85 | CA12 (0.63) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL15392142 | 0.85 | CA12 (0.63) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL17974302 | 0.84 | CA12 (0.53) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL21601467 | 0.84 | CA12 (0.69) | CA12CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968233-B2 | Monothiol mucolytic agents | PARION SCIENCES, INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. | 2019-01-31 | — | — | US | disclosed |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2016123335-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968233-B2 | Monothiol mucolytic agents | MUC1, HRH2, MAN2A1 | CA12 513/4885CA1 1466/4885CA2 2413/4885 |
| US-20190031679-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | CA12 588/4885CA1 1786/4885CA2 2639/4885 |
| US-20160222023-A1 | NOVEL MONOTHIOL MUCOLYTIC AGENTS | MUC1, MAN2A1, HRH2 | CA12 588/4885CA1 1786/4885CA2 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.