SCHEMBL179878

SCHEMBL179878

CC(CCC(=O)O)Sc1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 5/20 0.52
HPGD P15428 4/20 0.52
HSD17B10 Q99714 2/20 0.52
KMT2A Q03164 4/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 3/20 0.40
RAB9A P51151 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
TSHR P16473 1/20 0.40
ALOX15 P16050 1/20 0.40
PKM P14618 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
EHMT1 Q9H9B1 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28795540 0.93 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
Succinimide SCHEMBL25387343 0.89 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL16132816 0.85 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL1395632 0.85 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL7421417 0.84 SMN1; SMN2 (0.55) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL28118108 0.83 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL23235923 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL29139348 0.81 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL23235912 0.80 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A
SCHEMBL30733309 0.80 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2HPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3878861-B1 CL AND/OR CH1 MUTATED ANTIBODIES FOR DRUG CONJUGATION LONZA AG (CH) 2025-05-07 EP claimed
US-20240239885-A1 ANTIBODY CONJUGATE COMPRISING ANTI-P-CADHERIN ANTIBODY AND USES THEREOF WuXi Biologics Ireland Limited (IE) 2024-07-18 US claimed
US-20240156978-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2024-05-16 US claimed
WO-2024044550-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
US-20240043512-A1 EPITOPES OF ANTI-SERINE PROTEASE INHIBITOR KAZAL (SPIK) ANTIBODIES IMCARE BIOTECH LLC 2024-02-08 US claimed
EP-4313009-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME Angiex, Inc. (US) 2024-02-07 EP claimed
US-11866496-B2 Humanized anti-CD79B antibodies and immunoconjugates and methods of use GENENTECH, INC. (US) 2024-01-09 US claimed
EP-4294845-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2023-12-27 EP claimed
US-11833222-B2 CL and/or CH1 mutated antibodies for drug conjugation LONZA LTD (CH) 2023-12-05 US claimed
US-20230372518-A1 ANTIMITOTIC TETRAPEPTIDE-ANTIBODY CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2023-11-23 US claimed
WO-2008052187-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH. INC. (US) 2008-05-02 WO claimed
US-20080050310-A1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2008-02-28 US claimed
WO-2007140371-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2007-12-06 WO claimed
EP-1812465-A1 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES Genentech, Inc. (US) 2007-08-01 EP claimed
EP-1786838-A2 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR GENENTECH, INC. (US) 2007-05-23 EP claimed
WO-2006054961-A2 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES GENENTECH, INC. (US) 2006-05-26 WO claimed
WO-2006029183-A2 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR GENENTECH, INC. (US) 2006-03-16 WO claimed
US-20050272118-A1 Novel composition and methods for the treatment of immune related diseases GENENTECH, INC. 2005-12-08 US claimed
US-20050106644-A1 Compositions and methods for the diagnosis and treatment of tumor GENENTECH, INC. 2005-05-19 US claimed
US-20050107595-A1 Compositions and methods for the diagnosis and treatment of tumor GENENTECH, INC. 2005-05-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239885-A1 ANTIBODY CONJUGATE COMPRISING ANTI-P-CADHERIN ANTIBODY AND USES THEREOF CDH1, EPCAM, VIM ALDH1A1 964/4885SMN1; SMN2 4095/4885HPGD 2865/4885
US-20080050310-A1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR CD22, CD2BP2, CD2 ALDH1A1 404/4885SMN1; SMN2 3912/4885HPGD 3038/4885
US-11866496-B2 Humanized anti-CD79B antibodies and immunoconjugates and methods of use CD99, CD79B, CD47 ALDH1A1 2739/4885SMN1; SMN2 2389/4885HPGD 4019/4885
US-20230372518-A1 ANTIMITOTIC TETRAPEPTIDE-ANTIBODY CONJUGATES AND METHODS OF USING SAME TAP1, HM13, TMSB4X ALDH1A1 3942/4885SMN1; SMN2 1303/4885HPGD 4446/4885
US-20240156978-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME TM9SF4, TMSB4X, TM9SF2 ALDH1A1 2070/4885SMN1; SMN2 1107/4885HPGD 4348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.