Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | ATIC | P31939 | 2/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531201 | 0.90 | TTR (0.40) | TTRMEN1KMT2ATDP1LMNA | |
| SCHEMBL17988752 | 0.84 | MEN1 (0.45) | TTRMEN1KMT2ATDP1LMNA | |
| SCHEMBL14969392 | 0.83 | CYP1A2 (0.36) | TTRMEN1KMT2ATDP1LMNA | |
| SCHEMBL14823545 | 0.83 | FOLH1 (0.43) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL12146314 | 0.82 | MEN1 (0.39) | TTRMEN1KMT2ATDP1LMNA | |
| SCHEMBL14963000 | 0.80 | TDP1 (0.46) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL14823554 | 0.80 | TDP1 (0.40) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL19113835 | 0.79 | FOLH1 (0.38) | TTRMEN1KMT2ATDP1MAPT | |
| SCHEMBL14347674 | 0.79 | MEN1 (0.42) | MEN1KMT2ATDP1LMNAHTT | |
| SCHEMBL14883322 | 0.76 | MEN1 (0.42) | MEN1KMT2ATDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409923-B2 | Drug-fluorophore complex for specific detection of tumor cells | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-09 | — | — | US | disclosed |