Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988759 | 0.81 | MEN1 (0.51) | TDP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17988751 | 0.80 | TTR (0.42) | TDP1MAPTMEN1KMT2ALMNA | |
| Iodide SCHEMBL2845889 | 0.79 | MEN1 (0.65) | TDP1MAPTMEN1KMT2ALMNA | |
| Bromide SCHEMBL31674744 | 0.79 | MEN1 (0.65) | TDP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14963017 | 0.79 | KDM4E (0.38) | TDP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12146276 | 0.75 | LMNA (0.59) | TDP1MAPTMEN1KMT2ALMNA | |
| Iodide SCHEMBL20557372 | 0.72 | LMNA (0.48) | TDP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17918191 | 0.71 | MAPT (0.43) | TDP1MAPTMEN1KMT2ALMNA | |
| Iodide SCHEMBL20557975 | 0.70 | MAPT (0.46) | TDP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14347674 | 0.69 | MEN1 (0.42) | TDP1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835484-B2 | Naphthocyanines for use as contrast agents | ALAMEDICS GMBH & CO. KG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20130131354-A1 | Naphthocyanines for Use as Contrast Agents | AIAMEDICS GmbH & Co. KG (DE) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131354-A1 | Naphthocyanines for Use as Contrast Agents | NPM1, UACA, INCENP | TDP1 4815/4885MAPT 932/4885MEN1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.