Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16195355 | 0.93 | MEN1 (0.39) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14823545 | 0.86 | FOLH1 (0.43) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14347674 | 0.85 | MEN1 (0.42) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL1370729 | 0.84 | MAPT (0.43) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL6802279 | 0.80 | FOLH1 (0.42) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14823559 | 0.80 | CASP6 (0.34) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL14883322 | 0.80 | MEN1 (0.42) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL17988752 | 0.80 | MEN1 (0.45) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL17988751 | 0.80 | TTR (0.42) | TDP1MEN1MAPTKMT2ALMNA | |
| SCHEMBL1367336 | 0.78 | LMNA (0.61) | TDP1MEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013041117-A1 | DYES FOR LABELLING MOLECULAR LIGANDS | ILLUMINA CAMBRIGDE LTD. (GB) | 2013-03-28 | — | — | WO | disclosed |