Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180311 | 0.78 | ACHE (0.42) | — | |
| SCHEMBL180033 | 0.77 | PDE4D (0.36) | METAP1KDM4EABCB11ALDH1A1POLB | |
| SCHEMBL3685904 | 0.77 | ACHE (0.41) | — | |
| SCHEMBL3688423 | 0.75 | ACHE (0.41) | — | |
| SCHEMBL9957468 | 0.70 | ERBB2 (0.32) | KDM4EABCB11ALDH1A1POLBHTR1A | |
| SCHEMBL1583328 | 0.68 | METAP1 (0.40) | METAP1 | |
| SCHEMBL18393609 | 0.66 | MAPK1 (0.41) | ALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL19475118 | 0.65 | NLRP3 (0.38) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL5951525 | 0.62 | METAP1 (0.40) | METAP1 | |
| SCHEMBL30042078 | 0.62 | NLRP3 (0.36) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402353-B1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | BOREALIS AG (AT) | 2018-04-25 | — | — | EP | disclosed |
| EP-2402353-B1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | BOREALIS AG (AT) | 2018-04-25 | — | — | EP | disclosed |
| EP-2402354-B1 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2016-03-02 | — | — | EP | disclosed |
| EP-2402354-B1 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2016-03-02 | — | — | EP | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8933256-B2 | Catalysts | BOREALIS AG (AT) | 2015-01-13 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-8865848-B2 | Process for olefin polymerisation using group 4 metallocene as catalysts | BOREALIS AG (AT) | 2014-10-21 | — | — | US | disclosed |
| US-20130217845-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2013-08-22 | — | — | US | disclosed |
| US-20130217845-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2013-08-22 | — | — | US | disclosed |
| WO-2012001051-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012001051-A1 | PROCESS FOR OLEFIN POLYMERISATION USING GROUP 4 METALLOCENE AS CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012001052-A2 | CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012001052-A2 | CATALYSTS | BOREALIS AG (AT) | 2012-01-05 | — | — | WO | disclosed |
| EP-2402353-A1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402353-A1 | Group 4 metallocenes useful as catalysts for the polymerization of olefins | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402354-A1 | Process for olefin polymerisation using group 4 metallocene as catalysts | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402354-A1 | Process for olefin polymerisation using group 4 metallocene as catalysts | Borealis AG (AT) | 2012-01-04 | — | — | EP | disclosed |