SCHEMBL17989795

SCHEMBL17989795

c1ccc(-n2c3cc4c(cc3c3ccc5ccccc5c32)c2ccccc2n4-c2ccc3ccccc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ATM Q13315 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
F2 P00734 1/20 0.40
F10 P00742 1/20 0.40
PRSS1 P07477 1/20 0.40
HPGD P15428 1/20 0.34
PTPN1 P18031 2/20 0.33
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 2/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PDE7A Q13946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17990355 0.95 L3MBTL1 (0.50) KDM4EATML3MBTL1F2F10
SCHEMBL17989772 0.93 L3MBTL1 (0.55) KDM4EATML3MBTL1F2F10
SCHEMBL15073562 0.92 KDM4E (0.47) KDM4EATML3MBTL1F2F10
SCHEMBL15073626 0.92 KDM4E (0.47) KDM4EATML3MBTL1F2F10
SCHEMBL22868755 0.92 KDM4E (0.50) KDM4EATML3MBTL1F2F10
SCHEMBL22186451 0.92 ATM (0.39) KDM4EATML3MBTL1F2F10
SCHEMBL22186708 0.92 ATM (0.39) KDM4EATML3MBTL1F2F10
SCHEMBL22186450 0.91 KDM4E (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL22926972 0.91 KDM4E (0.44) KDM4EATML3MBTL1F2F10
SCHEMBL17989806 0.91 KDM4E (0.47) KDM4EATML3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-01-28 US disclosed
US-20160225992-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210028373-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, LIMS1 KDM4E 3066/4885ATM 2257/4885L3MBTL1 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.