Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894377 | 0.97 | SMN1; SMN2 (0.36) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL17484631 | 0.89 | — | — | |
| SCHEMBL5405071 | 0.83 | — | — | |
| SCHEMBL5419424 | 0.83 | — | — | |
| SCHEMBL5405095 | 0.80 | — | — | |
| SCHEMBL975019 | 0.77 | — | — | |
| SCHEMBL17991921 | 0.77 | LMNA (0.38) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL399613 | 0.76 | — | — | |
| SCHEMBL554799 | 0.76 | TSHR (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL304205 | 0.76 | TSHR (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354752-A1 | DE NOVO SYNTHESIZED GENE LIBRARIES | Twist Bioscience Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20160339409-A1 | DE NOVO SYNTHESIZED GENE LIBRARIES | Twist Bioscience Corporation | 2016-11-24 | — | — | US | disclosed |
| US-20160340672-A1 | DE NOVO SYNTHESIZED GENE LIBRARIES | Twist Bioscience Corporation | 2016-11-24 | — | — | US | disclosed |
| US-20160303535-A1 | DE NOVO SYNTHESIZED GENE LIBRARIES | Twist Bioscience Corporation | 2016-10-20 | — | — | US | disclosed |
| US-9409139-B2 | De novo synthesized gene libraries | Twist Bioscience Corporation (US) | 2016-08-09 | — | — | US | disclosed |