SCHEMBL20953588

SCHEMBL20953588

C/C(=C\c1cc(F)c(Oc2ccc(SNc3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c3)cc2)c(F)c1)C(=O)N=C(N)N

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC9A3 P48764 14/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23469959 0.86 SLC9A3 (0.51) SLC9A3
SCHEMBL13467244 0.86 SLC9A3 (0.64) SLC9A3
SCHEMBL17991934 0.83 SLC9A3 (0.57) SLC9A3
SCHEMBL23469853 0.83 SLC9A3 (0.57) SLC9A3
SCHEMBL24201220 0.83 SLC9A3 (0.36) SLC9A3
SCHEMBL23469997 0.82 SLC9A3 (0.52) SLC9A3
SCHEMBL22693314 0.80 SLC9A3 (0.59) SLC9A3
SCHEMBL23469885 0.80 SLC9A3 (0.50) SLC9A3
SCHEMBL2569406 0.79 SLC9A3 (0.67) SLC9A3
SCHEMBL13286035 0.79 SLC9A3 (0.67) SLC9A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230277523-A1 METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2023-09-07 — — US disclosed
US-10272079-B2 NHE3-binding compounds and methods for inhibiting phosphate transport ARDELYX, INC. (US) 2019-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10272079-B2 NHE3-binding compounds and methods for inhibiting phosphate transport SLC34A3, SLC34A2, SLC34A1 SLC9A3 4/4885
US-20230277523-A1 METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A3, SLC34A2, SLC34A1 SLC9A3 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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