Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991988 | 0.95 | STS (0.51) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL15399392 | 0.90 | MAPT (0.53) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17988702 | 0.87 | STS (0.45) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL15398873 | 0.84 | STS (0.66) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17991990 | 0.83 | MAPT (0.58) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17991989 | 0.83 | MAPT (0.61) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17991999 | 0.83 | MAPT (0.57) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17988695 | 0.82 | ALDH1A1 (0.55) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17991978 | 0.80 | MAPT (0.50) | MAPTALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL17988698 | 0.78 | STS (0.58) | MAPTALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |