Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12617577 | 1.00 | MGLL (0.45) | MGLLSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL1797987 | 0.90 | MGLL (0.41) | MGLLMEN1KMT2APOLBDRD2 | |
| SCHEMBL1799186 | 0.83 | PTGDR2 (0.54) | MEN1KMT2AP2RY1POLBLMNA | |
| SCHEMBL1801522 | 0.83 | PTGDR2 (0.54) | MEN1KMT2AP2RY1POLBLMNA | |
| SCHEMBL1801191 | 0.83 | PTGDR2 (0.54) | MEN1KMT2AP2RY1POLBLMNA | |
| SCHEMBL1800914 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL12618154 | 0.78 | PTGDR2 (0.53) | MEN1KMT2AP2RY1POLBLMNA | |
| SCHEMBL1797600 | 0.78 | PTGDR2 (0.53) | MEN1KMT2AP2RY1POLBLMNA | |
| SCHEMBL1799871 | 0.77 | PTGDR2 (0.59) | MEN1KMT2AP2RY1 | |
| SCHEMBL1799873 | 0.77 | PTGDR2 (0.59) | MEN1KMT2AP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951950-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-05-31 | — | — | US | disclosed |