Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194431 | 1.00 | SLC5A2 (0.47) | SLC5A2SLC5A1 | |
| SCHEMBL12363977 | 0.89 | SLC5A2 (0.48) | SLC5A2SLC5A1 | |
| SCHEMBL14209303 | 0.89 | SLC5A2 (0.48) | SLC5A2SLC5A1 | |
| SCHEMBL13483179 | 0.88 | SLC5A2 (0.53) | SLC5A2SLC5A1 | |
| SCHEMBL19415582 | 0.88 | SLC5A2 (0.53) | SLC5A2SLC5A1 | |
| SCHEMBL13568132 | 0.88 | SLC5A2 (0.53) | SLC5A2SLC5A1 | |
| SCHEMBL1551989 | 0.88 | SLC5A2 (0.53) | SLC5A2SLC5A1 | |
| SCHEMBL2861270 | 0.84 | SLC5A2 (0.46) | SLC5A2SLC5A1 | |
| SCHEMBL8227387 | 0.84 | SLC5A2 (0.42) | SLC5A2SLC5A1 | |
| SCHEMBL13412089 | 0.84 | SLC5A2 (0.42) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |
| US-7662790-B2 | Glucopyranosyl-substituted (heteroaryloxy-benzyl)-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-16 | — | — | US | disclosed |
| EP-1874787-B1 | GLUCOPYRANOSYL-SUBSTITUTED (HETEROARYLOXY-BENZYL)-BENZENE DERIVATIVES AS SGLT INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2007000445-A1 | GLUCOPYRANOSYL-SUBSTITUTED BENZYL-BENZENE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-04 | — | — | WO | disclosed |
| US-20070004648-A1 | Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture | HIMMELSBACH FRANK | 2007-01-04 | — | — | US | disclosed |
| US-20070004648-A1 | Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture | HIMMELSBACH FRANK | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004648-A1 | Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture | UGGT1, GYS2, UGT2B7 | SLC5A2 7/4885SLC5A1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.