Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | NEK2 | P51955 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025062 | 0.78 | MCL1 (0.50) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL14584326 | 0.78 | CYP1A2 (0.59) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL5487330 | 0.77 | MCL1 (0.62) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL17964122 | 0.77 | MCL1 (0.49) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL9816154 | 0.77 | MCL1 (0.73) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL29555314 | 0.74 | SIGMAR1 (0.63) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL27737084 | 0.74 | SIGMAR1 (0.63) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL2349 | 0.74 | SIGMAR1 (0.63) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL29364795 | 0.74 | SIGMAR1 (0.63) | MCL1KDM4EGAAMAPTSIGMAR1 | |
| SCHEMBL10067557 | 0.74 | CYP1A2 (0.50) | MCL1KDM4EGAAMAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016120403-A1 | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | GALECTO BIOTECH AB (DK) | 2016-08-04 | — | — | WO | disclosed |